[风湿性患者血清中针对心脏瓣膜成纤维细胞的抗体]
[Antibodies to heart valve fibroblasts in the sera of rheumatic patients].
作者信息
Danilova T A, Fedorova N M, Rassokhina I I
出版信息
Biull Eksp Biol Med. 1977 Mar;83(3):315-7.
PMID:851634
Abstract
The antibodies reactive in immunofluorescence with the fibroblasts of human and bovine heart valves were isolated from the rheumatic patients' sera with the aid of immunoadsorbent prepared from human heart valve tissue. No reaction between the antibodies and the fibroblasts of the interstitial connective tissue of the myocardium was observed. It seems that the fibroblasts of the heart valves and the myocardium contain different antigens; the presence of common antigenic components in human and bovine valve fibroblasts is shown.
摘要
借助由人心脏瓣膜组织制备的免疫吸附剂，从风湿性患者血清中分离出在免疫荧光中与人及牛心脏瓣膜成纤维细胞发生反应的抗体。未观察到这些抗体与心肌间质结缔组织的成纤维细胞之间有反应。似乎心脏瓣膜和成纤维细胞含有不同抗原；已表明人和牛瓣膜成纤维细胞中存在共同的抗原成分。
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