Giboda M, Loudová J, Smith J M, Gutvirth J
Institute of Parasitology, Academy of Sciences of Czech Republic, Ceské Budéjovice.
Trop Med Parasitol. 1993 Mar;44(1):55-6.
An active of imported malaria was carried out on 1432 foreign residents entering Czechoslovakia between 1986-1989. The survey group consisted of adult aged 18-35 years who arrived from malaria endemic regions. Of 660 people surveyed who were from regions of Africa south of the Sahara, 10% were positive for Plasmodium falciparum. Whereas, those arriving from South East Asia had a relatively low prevalence of malaria (2.6%), predominantly P. vivax. Of the 10% of cases testing positive for P. falciparum, 85% had less than 10,000 asexual stages/microliters of blood and 75% were asymptomatic carriers. By contrast, 93.8% of P. vivax/ovale infections were diagnosed because of the onset of symptoms. Both the frequency of seropositivity and the geometrical mean reciprocal titre (IgG), using P. falciparum antigen, were higher in those people arriving from Africa (79% and 1,307) compared with those arriving from S.E. Asia (44.4% and 628). Malaria was confirmed, by blood smear examination, in only 23.8% of the seropositive cohort. There was a positive correlation between the percentage of P. falciparum-positive blood smears and the level of antibody titre. There was no correlation between serum reactivity and level of parasitaemia.
1986年至1989年间,对1432名进入捷克斯洛伐克的外国居民进行了输入性疟疾的调查。调查对象为年龄在18至35岁之间、来自疟疾流行地区的成年人。在660名来自撒哈拉以南非洲地区的被调查者中,10%的人恶性疟原虫检测呈阳性。而来自东南亚的人疟疾患病率相对较低(2.6%),主要为间日疟原虫。在检测出恶性疟原虫阳性的病例中,85%的人每微升血液中的无性体阶段少于10000个,75%为无症状携带者。相比之下,93.8%的间日疟原虫/卵形疟原虫感染是因症状发作而被诊断出来的。使用恶性疟原虫抗原检测时,来自非洲的人血清阳性率和几何平均倒数滴度(IgG)均高于来自东南亚的人(分别为79%和1307,以及44.4%和628)。通过血涂片检查,仅在23.8%的血清阳性人群中确诊了疟疾。恶性疟原虫阳性血涂片的百分比与抗体滴度水平之间存在正相关。血清反应性与寄生虫血症水平之间无相关性。