Fisher J W
Armstrong Laboratory, Toxicology Division (OET), Wright-Patterson Air Force Base, OH 45433-6573.
Toxicol Lett. 1993 May;68(1-2):127-9. doi: 10.1016/0378-4274(93)90125-h.
Trichloroethylene (TCE) is a common and persistent environmental contaminant found in groundwater near most large cities and at Superfund landfill sites. In many cases, the groundwater is the primary source for water consumption. Because of the widespread distribution of TCE in the environment, a significant fraction of the population may ingest or inhale TCE over an extended period of time. Typically, environmental concentrations of TCE are in the ppb range. Health concerns for environmental exposure to TCE stem largely from positive outcomes in laboratory cancer bioassay studies with rodents at relatively high exposure concentrations. Epidemiological evidence that TCE is a human carcinogen is equivocal.
三氯乙烯（TCE）是一种常见且持久存在的环境污染物，在大多数大城市附近的地下水以及超级基金填埋场中都能找到。在许多情况下，地下水是主要的用水来源。由于TCE在环境中广泛分布，相当一部分人口可能在较长时间内摄入或吸入TCE。通常，环境中TCE的浓度处于十亿分比范围。对TCE环境暴露的健康担忧主要源于在相对高暴露浓度下对啮齿动物进行的实验室癌症生物测定研究中的阳性结果。关于TCE是人类致癌物的流行病学证据并不明确。
