Fuse H, Okumura M, Kazama T, Katayama T
Department of Urology, Toyama Medical and Pharmaceutical University, Japan.
Andrologia. 1993 May-Jun;25(3):153-7.
The resazurin reduction test was performed on semen samples from 83 untreated infertile and 9 pregnancy-confirmed fertile males, and the results were compared with other sperm parameters. The highest correlations with resazurin grade were found for motile sperm concentration (r = 0.65, P < 0.001), per cent motility (r = 0.58, P < 0.01), and percentage of swollen sperm (r = 0.57, P < 0.01). There were also significant but weak correlations between resazurin grade and both sperm concentration and linearity. There was a significant difference in the rate of positive tests between samples from normozoospermic and fertile males, and samples from patients exhibiting abnormal semen parameters (P < 0.001). These findings indicate that the resazurin test may be able to predict those males who may be fertile despite an abnormal semen analysis, and therefore, the test may be useful in the evaluation of the infertile patient as a part of a comprehensive male fertility assessment.
对83名未经治疗的不育男性和9名已确认怀孕的可育男性的精液样本进行了刃天青还原试验,并将结果与其他精子参数进行了比较。发现与刃天青分级相关性最高的是活动精子浓度(r = 0.65,P < 0.001)、活动率(r = 0.58,P < 0.01)和肿胀精子百分比(r = 0.57,P < 0.01)。刃天青分级与精子浓度和线性度之间也存在显著但较弱的相关性。正常精子症男性和可育男性的样本与精液参数异常患者的样本之间的阳性检测率存在显著差异(P < 0.001)。这些发现表明,刃天青试验可能能够预测那些尽管精液分析异常但仍可能具有生育能力的男性,因此,该试验作为男性生育能力综合评估的一部分,可能有助于不育患者的评估。