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Gamma radiation-induced differentiation on human neuroblastoma cells in culture.

作者信息

Rocchi P, Ferreri A M, Simone G, Granchi D, Nanni P, Frau A, Paolucci P, Paolucci G

机构信息

Istituto di Cancerologia, Università di Bologna, Italy.

出版信息

Anticancer Res. 1993 Mar-Apr;13(2):419-22.

PMID:8517657
Abstract

We have studied the effect of gamma radiation on differentiation in neuroblastoma cell lines AF8 and SJ-N-KP. Growth inhibition and morphological and biochemical differentiation have been examined following radiation exposure to 1-10 Gy. Gamma radiation induced marked growth inhibition and morphological differentiation in a dose-and time-dependent manner in both cell lines, and induced biochemical differentiation in AF8 cells.

摘要

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