Igarashi T, Sekine T, Sugimura H, Hayakawa H, Arayama T
Department of Paediatrics, Faculty of Medicine, University of Tokyo, Japan.
Pediatr Nephrol. 1993 Jun;7(3):292-3. doi: 10.1007/BF00853226.
We describe a 12-year-old boy with renal hypouricaemia who presented with acute renal failure after a 6-h sports training session. Back and loin pain were noted at presentation. Although serum creatinine and blood urea nitrogen were elevated, the serum uric acid concentration was normal (2.6 mg/dl). This decreased to 0.3 mg/dl after recovery. The pyrazinamide and probenecid tests revealed that the cause of renal hypouricaemia in this patient was totally defective uric acid reabsorption. Acute renal failure after exercise is a rare but serious complication in paediatric patients with renal hypouricaemia.
我们描述了一名12岁的肾性低尿酸血症男孩，他在进行6小时的体育训练后出现急性肾衰竭。就诊时发现有背部和腰部疼痛。虽然血清肌酐和血尿素氮升高，但血清尿酸浓度正常（2.6mg/dl）。恢复后该值降至0.3mg/dl。吡嗪酰胺和丙磺舒试验表明，该患者肾性低尿酸血症的原因是尿酸重吸收完全缺陷。运动后急性肾衰竭在患有肾性低尿酸血症的儿科患者中是一种罕见但严重的并发症。
