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一名患有糖尿病的英国患者的播散性组织胞浆菌病。

Disseminated histoplasmosis in an English patient with diabetes mellitus.

作者信息

Jariwalla A, Tulloch B R, Fox H, Kelly J, Davies R

出版信息

Br Med J. 1977 Apr 16;1(6067):1002-4. doi: 10.1136/bmj.1.6067.1002.

DOI:10.1136/bmj.1.6067.1002
PMID:851818
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1605969/
Abstract

Histoplasma capsulatum is not endemic in Britain. We report a case of disseminated histoplasmosis in an English man who had not ventured out of northern Europe for 30 years. The disease presented as painful mouth ulcers and hepatosplenomegaly six months after he had developed maturity-onset diabetes. The origin of the infecting fungus may have been from within the United Kingdom or alternatively it may have existed as an intraoral saprophyte for over 30 years.

摘要

荚膜组织胞浆菌在英国并非地方性流行病菌。我们报告一例播散性组织胞浆菌病病例，患者为一名英国男子，他已有30年未曾离开北欧。该病表现为在他患成年型糖尿病6个月后出现疼痛性口腔溃疡和肝脾肿大。感染真菌的来源可能是在英国国内，或者它可能已作为口腔内腐生菌存在超过30年了。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/b031eff3147f/brmedj00458-0023-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/b81ac623253f/brmedj00458-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/30bb7c6048a0/brmedj00458-0023-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/ef8c840ba22a/brmedj00458-0023-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/b798250fd8e9/brmedj00458-0023-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/b031eff3147f/brmedj00458-0023-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/b81ac623253f/brmedj00458-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/30bb7c6048a0/brmedj00458-0023-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/ef8c840ba22a/brmedj00458-0023-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/b798250fd8e9/brmedj00458-0023-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ba/1605969/b031eff3147f/brmedj00458-0023-d.jpg

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本文引用的文献

1
Progressive disseminated histoplasmosis as seen in adults.成人播散性组织胞浆菌病。
Am J Med. 1970 May;48(5):629-36. doi: 10.1016/0002-9343(70)90014-8.
2
Progressive disseminated histoplasmosis. A prospective study of 26 patients.进行性播散性组织胞浆菌病。对26例患者的前瞻性研究。
Ann Intern Med. 1972 Apr;76(4):557-65. doi: 10.7326/0003-4819-76-4-557.
3
Pathogenesis and clinical spectrum of histoplasmosis.组织胞浆菌病的发病机制与临床谱
BMJ Case Rep. 2010 Nov 5;2010:bcr.06.2010.3120. doi: 10.1136/bcr.06.2010.3120.
South Med J. 1973 Jan;66(1):13-25. doi: 10.1097/00007611-197301000-00004.