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[肺隐孢子虫病与艾滋病。1例病例报告及文献复习]

[Pulmonary cryptosporidiosis and AIDS. Presentation of a case and review of the literature].

作者信息

Brea Hernando A J, Bandrés Franco E, Mosquera Lozano J D, Lantero Benedito M, Ezquerra Lezcano M

机构信息

Servicio de Medicina Interna, Hospital San Millán, Logroño, La Rioja.

出版信息

An Med Interna. 1993 May;10(5):232-6.

PMID:8518339
Abstract

Pulmonary cryptosporidiasis is a rare disease. However, following the advent of the acquired immunodeficiency syndrome (AIDS), this rare pathology infection by Cryptosporidium and we conduct a literature review. The Cryptosporidium can be detected with the routine technique used for the identification of mycobacterias in sputum: Zichl-Neelsen, auramine O, Kinyoun, etc. The most frequent sympthomatology includes chronic cough (91%), fever (59%) and dyspnea (64%). In 78% of cases, several respiratory infectious agents coexist, mainly P. carinii (47%) and Cytomegalovirus (41%). In 76% of cases, the infection is followed by diarrhea, detecting Cryptosporidium in the feces of 80% of these patients. The most frequent cause of death is respiratory failure. The radiologic evidences are not specific. The OKT4+/OKT8+ ratio has an average value of 0.3 (0.05-0.9). There is not any treatment truly effective.

摘要

肺隐孢子虫病是一种罕见疾病。然而,随着获得性免疫缺陷综合征(艾滋病)的出现,这种由隐孢子虫引起的罕见病理感染情况出现了,我们进行了一项文献综述。隐孢子虫可以通过用于痰液中分枝杆菌鉴定的常规技术检测出来:萋-尼氏染色法、金胺O染色法、金扬氏染色法等。最常见的症状包括慢性咳嗽(91%)、发热(59%)和呼吸困难(64%)。在78%的病例中,几种呼吸道感染病原体同时存在,主要是卡氏肺孢子虫(47%)和巨细胞病毒(41%)。在76%的病例中,感染后会出现腹泻,在这些患者中80%的粪便中可检测到隐孢子虫。最常见的死亡原因是呼吸衰竭。放射学证据不具特异性。OKT4+/OKT8+比值的平均值为0.3(0.05 - 0.9)。没有任何真正有效的治疗方法。

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