Fisseha B, Petros B, WoldeMichael T
Department of Infectious and other Diseases Research, Ethiopian Health and Nutrition Research Institute, Addis Ababa, Ethiopia.
East Afr Med J. 1998 Feb;75(2):100-1.
Previous studies in other African countries have shown high prevalences of Isospora belli and Cryptosporidium parvum infections in acquired immunodeficiency syndrome (AIDS) patients with chronic diarrhoea. However, there is lack of information regarding these infectious agents in Ethiopian AIDS patients. Thus, this investigation has been aimed at determining the prevalence of Cryptosporidium and other related gastrointestinal parasites in AIDS patients with diarrhoea in seven Addis Ababa hospitals. Stool specimens from 246 clinically diagnosed AIDS patients were parasitologically screened for parasitic infections constituting HIV-negative with diarrhoea and HIV-positive without diarrhoea control groups. A variety of intestinal protozoa and helminths were found in 50% of AIDS patients and 42% of the controls. Cryptosporidiosis was detected in 38(25.9%), Isosporiasis in two (1.4%), and Blastocystosis in one (0.7%) of the AIDS patients with diarrhoea. The occurrence of cryptosporidiosis among the AIDS patients and possible explanation of the increasingly high study subjects with diarrhoea but without identifiable parasites is discussed.
此前在其他非洲国家开展的研究表明，患有慢性腹泻的获得性免疫缺陷综合征（AIDS）患者中，贝氏等孢球虫和微小隐孢子虫感染的患病率很高。然而，埃塞俄比亚艾滋病患者中关于这些传染源的信息却很匮乏。因此，本调查旨在确定亚的斯亚贝巴七家医院中腹泻艾滋病患者隐孢子虫及其他相关胃肠道寄生虫的患病率。对246例临床诊断为艾滋病的患者的粪便标本进行寄生虫学筛查，以检测构成HIV阴性伴腹泻及HIV阳性无腹泻对照组的寄生虫感染情况。在50%的艾滋病患者和42%的对照组中发现了多种肠道原生动物和蠕虫。腹泻的艾滋病患者中，38例（25.9%）检测出隐孢子虫病，2例（1.4%）检测出等孢球虫病，1例（0.7%）检测出芽囊原虫病。本文讨论了艾滋病患者中隐孢子虫病的发生情况，以及对腹泻但未发现可识别寄生虫的研究对象数量日益增加的可能解释。
