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Are hepatocyte growth factor-like protein and macrophage stimulating protein the same protein?肝细胞生长因子样蛋白和巨噬细胞刺激蛋白是同一种蛋白吗?
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Macrophage colony-stimulating factor-, granulocyte-macrophage colony-stimulating factor-, or IL-3-dependent survival of macrophages, but not proliferation, requires the expression of p21(Waf1) through the phosphatidylinositol 3-kinase/Akt pathway.巨噬细胞集落刺激因子、粒细胞-巨噬细胞集落刺激因子或白细胞介素-3依赖的巨噬细胞存活(而非增殖)需要通过磷脂酰肌醇3激酶/蛋白激酶B途径表达p21(Waf1)。
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Purity of biological products: related and unrelated impurities.
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Mutation of Cys672 allows recombinant expression of activatible macrophage-stimulating protein.半胱氨酸672的突变可实现可激活巨噬细胞刺激蛋白的重组表达。
J Biol Chem. 1997 Jun 13;272(24):15053-6. doi: 10.1074/jbc.272.24.15053.

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Biomedicines. 2015 Feb 4;3(1):110-123. doi: 10.3390/biomedicines3010110.
3
Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis.肝细胞生长因子样蛋白是早期乳腺导管形态发生的正向调节因子。
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The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse.Ron/STK受体酪氨酸激酶对小鼠植入前发育至关重要。
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Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice.小鼠中肝细胞生长因子样蛋白靶向失活的生物学效应
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Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP).纤溶酶原相关生长因子(肝细胞生长因子/散射因子和HGF1/巨噬细胞刺激蛋白)的分子进化与结构域结构
Protein Sci. 1994 Dec;3(12):2378-94. doi: 10.1002/pro.5560031222.

本文引用的文献

1
Molecular cloning and expression of human hepatocyte growth factor.人肝细胞生长因子的分子克隆与表达
Nature. 1989 Nov 23;342(6248):440-3. doi: 10.1038/342440a0.
2
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product.肝细胞生长因子受体被鉴定为c-met原癌基因产物。
Science. 1991 Feb 15;251(4995):802-4. doi: 10.1126/science.1846706.
3
Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET.肝细胞生长因子(HGF)刺激原癌基因c-MET编码的受体的酪氨酸激酶活性。
Oncogene. 1991 Apr;6(4):501-4.
4
Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity.巨噬细胞刺激蛋白:纯化、部分氨基酸序列及细胞活性
J Exp Med. 1991 May 1;173(5):1227-34. doi: 10.1084/jem.173.5.1227.
5
Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor.人类3号染色体上DNF15S2基因座的特征:鉴定一个编码与肝细胞生长因子具有同源性的四个kringle结构域的基因。
Biochemistry. 1991 Oct 8;30(40):9768-80. doi: 10.1021/bi00104a029.
6
Scatter factor and hepatocyte growth factor: activities, properties, and mechanism.分散因子与肝细胞生长因子:活性、特性及作用机制
Cell Growth Differ. 1992 Jan;3(1):11-20.
7
Hepatocyte growth factor.肝细胞生长因子
Hepatology. 1992 Jan;15(1):149-55. doi: 10.1002/hep.1840150125.

Are hepatocyte growth factor-like protein and macrophage stimulating protein the same protein?

作者信息

Bezerra J A, Han S, Danton M J, Degen S J

机构信息

Division of Basic Science Research, Children's Hospital Research Foundation, Cincinnati, Ohio 45229-2899.

出版信息

Protein Sci. 1993 Apr;2(4):666-8. doi: 10.1002/pro.5560020416.

DOI:10.1002/pro.5560020416
PMID:8518737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2142360/
Abstract
摘要