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睾酮对大鼠肝脏和血清中甘油三酯水平及脂肪酸组成的影响。

Effects of testosterone on triglyceride levels and fatty acid composition in the liver and serum of the rat.

作者信息

Cinci G, Pizzichini M, Pandolfi M L, Porcelli B, Marinello E, Pagani R

机构信息

Institute of Biochemistry and Enzymology, Siena, Italia.

出版信息

C R Acad Sci III. 1993;316(2):97-103.

PMID:8518968
Abstract

Triacyglycerol content and fatty acid composition has been determined in the liver and in the serum of normal, castrated and testosterone-treated rats. Most variations were found in UNS/SAT ratio, which were referred to an action of the hormone on the delta 5-delta 6-delta 9 desaturases. Results concerning the behaviour of delta 9 desaturase suggest that either different isoenzymes are involved or that a single enzyme undergoes a different regulation according to the substrate involved.

摘要

已测定正常、去势及经睾酮处理的大鼠肝脏和血清中的甘油三酯含量及脂肪酸组成。大部分变化见于不饱和/饱和脂肪酸比值,这归因于激素对δ5-δ6-δ9去饱和酶的作用。关于δ9去饱和酶行为的结果表明,要么涉及不同的同工酶,要么单一酶根据所涉及的底物受到不同的调节。

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