Albers S E, Brozena S J, Fenske N A
Department of Internal Medicine, University of South Florida, College of Medicine, Tampa 33612.
Cutis. 1993 Jun;51(6):445-6.
Kwashiorkor is part of the spectrum of protein-energy malnutrition. The condition results from a lack of nutritional protein coupled with carbohydrate excess. Protein malnutrition is much more common in the Third World; however, it is also the most common form of nutritional deficiency among hospitalized patients in the United States. Cutaneous clues to the diagnosis of protein deficiency include the "flag sign," hypochromotrichia, alopecia, "crazy pavement" dermatosis, pallor, and glossitis. Systemic manifestations include peripheral edema, liver disease, neurologic changes, diarrhea, weight loss, and hypoalbuminemia. We report here a case of profound kwashiorkor in a nonhospitalized patient who presented with multiple cutaneous and systemic findings indicative of protein malnutrition.
夸休可尔症是蛋白质 - 能量营养不良症的一种。该病是由于缺乏营养性蛋白质并伴有碳水化合物过量所致。蛋白质营养不良在第三世界更为常见;然而,它也是美国住院患者中最常见的营养缺乏形式。蛋白质缺乏诊断的皮肤线索包括“旗状征”、低色素性毛发、脱发、“马赛克”样皮肤病、苍白和舌炎。全身表现包括外周水肿、肝病、神经学改变、腹泻、体重减轻和低白蛋白血症。我们在此报告一例非住院患者的严重夸休可尔症病例,该患者出现了多种表明蛋白质营养不良的皮肤和全身表现。