Tucker L B
Division of Pediatric Rheumatology, Floating Hospital for Children, New England Medical Center, Boston, MA 02111, USA.
Curr Opin Rheumatol. 1995 Sep;7(5):419-24. doi: 10.1097/00002281-199509000-00010.
Often, a child is referred for evaluation to a pediatric rheumatologist and found to have a nonrheumatologic disorder. Infections constitute an important group of disorders with potential musculoskeletal system involvement. Reactive arthritis subsequent to infection with Yersinia is discussed, as well as reactive arthritis seen in the course of cystic fibrosis. Musculoskeletal manifestations of tuberculosis and brucellosis are reviewed. The continued presence of acute rheumatic fever in the United States has been documented, but the clinical spectrum of the disease appears to be changing over time. A variety of inherited syndromes may involve the musculoskeletal system, either primarily or as a minor manifestation. The bony dysplasias, another group of disorders, result from abnormal collagen structure and affect musculoskeletal development; clinical findings and new genetic information is reviewed. Descriptions of several rare syndromes (eg, hyaline fibromatosis and hypertrophic osteoarthropathy) also are reviewed here.
通常，儿童会被转介给儿科风湿病专家进行评估，结果发现患有非风湿性疾病。感染是一组重要的疾病，可能累及肌肉骨骼系统。本文将讨论耶尔森菌感染后的反应性关节炎，以及囊性纤维化病程中出现的反应性关节炎。还将回顾结核病和布鲁氏菌病的肌肉骨骼表现。美国急性风湿热持续存在已有记录，但随着时间的推移，该疾病的临床谱似乎正在发生变化。多种遗传性综合征可能主要或作为次要表现累及肌肉骨骼系统。骨发育异常是另一类疾病，由胶原蛋白结构异常引起，影响肌肉骨骼发育；本文将回顾其临床发现和新的基因信息。这里还将回顾几种罕见综合征（如透明纤维瘤病和肥厚性骨关节病）的描述。
