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Measles virus replication in neural cells.

作者信息

Johnston I C, Dunster L M, Schneider-Schaulies J, Schneider-Schaulies S

机构信息

Institute for Virology, Würzburg, Germany

出版信息

Trends Microbiol. 1995 Sep;3(9):361-5. doi: 10.1016/s0966-842x(00)88976-3.

Abstract

Measles virus gene expression is attenuated in neural cells by mechanisms that affect both viral transcription and translation. Host enzymes that hypermutate viral genes, and those induced by cytokines, may act cooperatively to slow viral replication and to favor persistent measles virus infections in the human central nervous system.

摘要

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