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[免疫参数在评估有害物质影响中的信息含量]

[Information content of immunologic parameters in the evaluation of the effects of hazardous substances].

作者信息

Litovskaia A V, Sadovskiĭ V V, Vifleemskiĭ A B

出版信息

Med Tr Prom Ekol. 1995(9):30-3.

PMID:8520912
Abstract

Clinical and immunologic examination including 1 and 2 level tests covered 429 staffers of chemical enterprises and 1122 of those engaged into microbiological synthesis of proteins, both the groups exposed to some irritating gases and isocyanates. Using calculation of Kulbak's criterion, the studies selected informative parameters to diagnose immune disturbances caused by occupational hazards. For integral evaluation of immune state, the authors applied general immunologic parameter, meanings of which can serve as criteria for early diagnosis of various immune disorders and for definition of risk groups among industrial workers exposed to occupational biologic and chemical hazards.

摘要

临床和免疫学检查,包括一级和二级检测,涵盖了429名化工企业员工以及1122名从事蛋白质微生物合成工作的人员,这两组人员均暴露于某些刺激性气体和异氰酸酯中。通过计算库尔巴克准则,这些研究选取了信息参数来诊断由职业危害引起的免疫紊乱。为了对免疫状态进行综合评估,作者应用了一般免疫学参数,其意义可作为各种免疫紊乱早期诊断的标准以及确定暴露于职业生物和化学危害的产业工人中危险群体的依据。

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