Brown P, Nolph K D
Clin Chim Acta. 1977 Apr 1;76(1):103-12. doi: 10.1016/0009-8981(77)90123-1.
Peritoneal inulin clearance during peritoneal dialysis is a useful indicator of efficiency of removal of larger solutes. Peritoneal dialysis solutions usually contain high glucose concentrations that interfere with the chemical measurements of inulin concentration. In these studies, inulin recoveries in simple glucose and peritoneal dialysis solutions with three chemical methods were compared; all methods reportedly were subject to minimal glucose interference. The findings showed one method subject to minimal and predictable glucose interference in all solutions tested. For two methods, interference in peritoneal dialysis solutions exceeded that predicted from glucose alone; this unexpected interference was shown to most likely result from carmalized glucose subsequent to the routine autoclaving of peritoneal dialysis solutions.
腹膜透析期间的腹膜菊粉清除率是清除较大溶质效率的一个有用指标。腹膜透析液通常含有高浓度葡萄糖，这会干扰菊粉浓度的化学测量。在这些研究中，比较了三种化学方法在单纯葡萄糖溶液和腹膜透析液中的菊粉回收率；据报道，所有方法受到的葡萄糖干扰都最小。研究结果表明，有一种方法在所有测试溶液中受到的葡萄糖干扰最小且可预测。对于另外两种方法，腹膜透析液中的干扰超过了仅由葡萄糖预测的干扰；这种意外的干扰最有可能是由于腹膜透析液常规高压灭菌后产生的焦糖化葡萄糖所致。
