Nolph K D, Rubin J, Wiegman D L, Harris P D, Miller F N
Nephron. 1979;24(1):34-40.
Peritoneal clearances were measured in multiple patients with different types of peritoneal dialysis solution to assess the effects of pH, choice of buffer anion (acetate versus lactate), and the effects of nitroprusside (a vasodilator) in combination with different buffer anions and varying pH. The studies show no differences in peritoneal clearances at very low solution pH (less than 6 as is commonly available) as compared to a pH nearer to 7 or above. There were no diffences between solutions with acetate as compared to those with acetate. Nitroprusside significantly increased clearances in all solutions to a similar extent.
对多名使用不同类型腹膜透析液的患者测量腹膜清除率，以评估pH值、缓冲阴离子的选择（醋酸盐与乳酸盐）以及硝普钠（一种血管扩张剂）与不同缓冲阴离子和不同pH值联合使用的效果。研究表明，与接近或高于7的pH值相比，在非常低的溶液pH值（低于常见的6）下，腹膜清除率没有差异。醋酸盐溶液与乳酸盐溶液之间没有差异。硝普钠在所有溶液中均显著提高清除率，且提高程度相似。
