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Microwave induced alteration in the neuron specific enolase gene expression.

作者信息

Verma M, Dutta S K

机构信息

Department of Biology, Howard University, Washington, DC 20059, USA.

出版信息

Cancer Biochem Biophys. 1993 Sep;13(4):239-44.

PMID:8521373
Abstract

Exposure of pNGE7, a recombinant clone containing the coding and regulatory sequences for the expression of neuron specific enolase gene, cells to electromagnetic radiations (915 MHz, 16 Hz AM, SAR 0.05 mW/kg) resulted in the elevation of neuron specific enolase (NSE), a diagnostic marker for neuron and lung cancer. Using ion-exchange chromatography we separated the neuron specific enolase activity from the non-neuronal enolase (NNE) activity and observed an alteration in the expression of neuron specific enolase and non-neuronal enolase. The clinical applications of the present studies have been discussed.

摘要

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