Zheng W, Yang G C, Godwin T A, Caputo T A, Zuna R E
Department of Pathology, Cornell University Medical College, NY, USA.
Hum Pathol. 1995 Dec;26(12):1385-8. doi: 10.1016/0046-8177(95)90307-0.
Mucinous differentiation of endocervical type has been well documented in endometrial carcinoma. However, we describe an unusual case of adenocarcinoma of the endometrium showing diffuse histological, immunohistochemical, and ultrastructural evidence of intestinal differentiation. Although intestinal differentiation has been described in mesodermally derived tissues including endocervix, ovary, and urinary tract, it has not been reported in normal endometrium. One previous case has been reported showing this pattern in endometrial carcinoma. Possible histogenetic mechanisms of this pattern are discussed.
子宫内膜癌中宫颈内膜型黏液分化已有充分记载。然而，我们描述了一例不寻常的子宫内膜腺癌病例，其显示出弥漫性的组织学、免疫组化及超微结构证据表明存在肠化生。尽管在包括宫颈内膜、卵巢及泌尿道等中胚层来源组织中已描述过肠化生，但在正常子宫内膜中尚未见报道。此前曾有一例子宫内膜癌呈现此模式的报道。本文讨论了这种模式可能的组织发生机制。
