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一例女性生殖道同步发生黏液性化生和肿瘤且无STK11或KRAS突变的病例。

A case of synchronous mucinous metaplasia and neoplasia of the female genital tract without an STK11 or KRAS mutation.

作者信息

Nagahama Kiyotaka, Yamanaka Shoji, Nakayama Takashi, Tokinaga Aya, Asai-Sato Mikiko, Miyagi Etsuko, Tanaka Reiko, Furuya Mitsuko

机构信息

Department of Pathology, Yokohama City University School of Medicine, Japan.

Department of Obstetrics and Gynecology, Yokohama City University School of Medicine, Japan.

出版信息

Gynecol Oncol Case Rep. 2013 Feb 18;5:4-5. doi: 10.1016/j.gynor.2013.02.005. eCollection 2013.

DOI:10.1016/j.gynor.2013.02.005
PMID:24371681
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3862322/
Abstract

► Synchronous mucinous metaplasia and neoplasia of the female genital tract (SMMN-FGT) is a rare mucinous lesion. ► This is the first case of SMMN-FGT with DNA sequencing of STK11 and KRAS, but no mutation was identified.

摘要

► 女性生殖道同步性黏液化生和肿瘤形成(SMMN-FGT)是一种罕见的黏液性病变。

► 这是首例对STK11和KRAS进行DNA测序的SMMN-FGT病例,但未发现突变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d233/3862322/ce536b4aa94a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d233/3862322/ce536b4aa94a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d233/3862322/ce536b4aa94a/gr1.jpg

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本文引用的文献

1
Papillary mucinous metaplasia of the endometrium as a possible precursor of endometrial mucinous adenocarcinoma.子宫内膜乳头状黏液性化生可能是子宫内膜黏液性腺癌的前驱病变。
Mod Pathol. 2012 Nov;25(11):1496-507. doi: 10.1038/modpathol.2012.113. Epub 2012 Jul 6.
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Reappraisal of synchronous and multifocal mucinous lesions of the female genital tract: a close association with gastric metaplasia.女性生殖道同步性和多灶性黏液性病变的重新评估:与胃化生密切相关。
Histopathology. 2009 Jan;54(2):184-91. doi: 10.1111/j.1365-2559.2008.03202.x.
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Atypical mucinous metaplasia and intraepithelial neoplasia of the female genital tract--a case report and review of the literature.
女性生殖道同步黏液化生与肿瘤形成(SMMN-FGT):一例病例报告及文献综述
Exp Ther Med. 2022 Dec 19;25(2):73. doi: 10.3892/etm.2022.11772. eCollection 2023 Feb.
女性生殖道非典型黏液性化生及上皮内瘤变——1例病例报告并文献复习
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Hum Mutat. 2005 Oct;26(4):291-7. doi: 10.1002/humu.20222.
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An unusual admixture of neoplastic and metaplastic lesions of the female genital tract in the Peutz-Jeghers Syndrome.黑斑息肉综合征中女性生殖道肿瘤性与化生性病损的一种罕见混合情况。
Gynecol Oncol. 2004 Jan;92(1):337-42. doi: 10.1016/j.ygyno.2003.10.005.
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Mutations in the STK11 gene characterize minimal deviation adenocarcinoma of the uterine cervix.STK11基因的突变是子宫颈微小偏离腺癌的特征。
Lab Invest. 2003 Jan;83(1):35-45. doi: 10.1097/01.lab.0000049821.16698.d0.
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Mucinous adenocarcinoma of the endometrium with intestinal differentiation: a case report.伴有肠化生的子宫内膜黏液腺癌:一例报告
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