• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Topical treatment of early cutaneous T-cell lymphoma.

作者信息

Ramsay D L, Meller J A, Zackheim H S

机构信息

New York University Medical Center, New York, USA.

出版信息

Hematol Oncol Clin North Am. 1995 Oct;9(5):1031-56.

PMID:8522483
Abstract

The two major topical treatment modalities for cutaneous T-cell lymphoma (CTCL) are mechlorethamine (nitrogen mustard) and topical carmustine (BCNU). Topical mechorethamine hydrochloride has been used since the late 1950s as therapy for CTCL. Topical BCNU solution is a highly effective treatment for early stage mycosis fungoides. This article describes these two modalities.

摘要

相似文献

1
Topical treatment of early cutaneous T-cell lymphoma.
Hematol Oncol Clin North Am. 1995 Oct;9(5):1031-56.
2
Treatment of cutaneous T-cell lymphoma.皮肤T细胞淋巴瘤的治疗
Semin Dermatol. 1994 Sep;13(3):207-15.
3
Unilesional cutaneous T-cell lymphoma: clinical features, therapy, and follow-up of 10 patients with a treatment-responsive mycosis fungoides variant.
J Am Acad Dermatol. 2000 Feb;42(2 Pt 1):283-5. doi: 10.1016/S0190-9622(00)90140-3.
4
Topical chemotherapy of mycosis fungoides.蕈样肉芽肿的局部化疗。
Cutis. 1979 Nov;24(5):543-6.
5
Mechlorethamine gel for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma.氮芥凝胶用于IA期和IB期蕈样肉芽肿型皮肤T细胞淋巴瘤的局部治疗。
Expert Rev Clin Pharmacol. 2014 Sep;7(5):591-7. doi: 10.1586/17512433.2014.944500. Epub 2014 Jul 28.
6
Clinical experience: practical management of five patients with cutaneous T-cell lymphoma (CTCL)-related symptoms.
Semin Oncol. 2006 Feb;33(1 Suppl 3):S26-32. doi: 10.1053/j.seminoncol.2005.12.020.
7
Cutaneous T cell lymphoma: update of treatment.皮肤T细胞淋巴瘤:治疗进展
Dermatology. 1999;199(2):102-5. doi: 10.1159/000018214.
8
Treatment of early-stage mycosis fungoides with twice-weekly applications of mechlorethamine and topical corticosteroids: a prospective study.每周两次应用氮芥和外用皮质类固醇治疗早期蕈样肉芽肿:一项前瞻性研究。
Arch Dermatol. 2005 Sep;141(9):1117-20. doi: 10.1001/archderm.141.9.1117.
9
Allergic contact dermatitis from topical carmustine.局部应用卡莫司汀引起的变应性接触性皮炎。
Contact Dermatitis. 2000 Feb;42(2):112.
10
Bexarotene gel: a new skin-directed treatment option for cutaneous T-cell lymphomas.贝沙罗汀凝胶:皮肤T细胞淋巴瘤的一种新的皮肤定向治疗选择。
J Drugs Dermatol. 2003 Apr;2(2):155-67.

引用本文的文献

1
Mechlorethamine Hydrochloride Gel in the Treatment of Mycosis Fungoides-Type Cutaneous T-Cell Lymphoma (MF-CTCL): A Focus on Patient Selection and Special Considerations.盐酸氮芥凝胶治疗蕈样肉芽肿型皮肤T细胞淋巴瘤(MF-CTCL):聚焦患者选择及特殊考量
Cancer Manag Res. 2022 Nov 22;14:3271-3279. doi: 10.2147/CMAR.S351420. eCollection 2022.
2
The PROVe Study: US Real-World Experience with Chlormethine/Mechlorethamine Gel in Combination with Other Therapies for Patients with Mycosis Fungoides Cutaneous T-Cell Lymphoma.PROVe 研究:氯苯丁二氮䓬/美法仑凝胶联合其他疗法治疗蕈样肉芽肿皮肤 T 细胞淋巴瘤患者的美国真实世界经验。
Am J Clin Dermatol. 2021 May;22(3):407-414. doi: 10.1007/s40257-021-00591-x. Epub 2021 Mar 3.
3
Successful Use of the 308-nm Excimer Laser in Early Patch Stage Mycosis Fungoides.
308纳米准分子激光在蕈样肉芽肿早期斑片期的成功应用。
J Lasers Med Sci. 2019 Summer;10(3):251-253. doi: 10.15171/jlms.2019.40. Epub 2019 Jul 6.
4
Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report.盐酸氮芥致急性呼吸衰竭和骨髓抑制:一例报告
Exp Ther Med. 2015 Oct;10(4):1293-1296. doi: 10.3892/etm.2015.2664. Epub 2015 Jul 29.
5
Topical chemotherapy in cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine, 0.02%, gel in mycosis fungoides.皮肤 T 细胞淋巴瘤的局部化疗:一项新型氮芥,0.02%,凝胶治疗蕈样肉芽肿的疗效和安全性的随机、对照、多中心试验的阳性结果。
JAMA Dermatol. 2013 Jan;149(1):25-32. doi: 10.1001/2013.jamadermatol.541.
6
Phase I clinical trial of O6-benzylguanine and topical carmustine in the treatment of cutaneous T-cell lymphoma, mycosis fungoides type.O6-苄基鸟嘌呤与局部用卡莫司汀治疗蕈样肉芽肿型皮肤T细胞淋巴瘤的I期临床试验
Arch Dermatol. 2012 May;148(5):613-20. doi: 10.1001/archdermatol.2011.2797.
7
Evaluation of T-cell receptor gene rearrangements in patients with recurrent patch/plaque (T2) CTCL (mycosis fungoides).复发性斑片/斑块状(T2)蕈样肉芽肿(皮肤T细胞淋巴瘤)患者T细胞受体基因重排的评估
Yale J Biol Med. 1999 Nov-Dec;72(6):365-75.