Rodriguez R, Dyer P D
Allergy/Immunization Clinic, Fitzsimons Army Medical Center, Aurora, Colorado 80045-5001, USA.
J Gen Intern Med. 1995 Sep;10(9):511-2. doi: 10.1007/BF02602403.
Indications for pneumococcal polysaccharide revaccination include highest-risk patients vaccinated more than six years previously, but there is controversy regarding revaccination of patients with chronic medical conditions and revaccination of the elderly. The object of the study was to investigate whether revaccination with the pneumococcal polysaccharide vaccine would cause significant adverse reactions. 151 patients were revaccinated and completed a questionnaire concerning the 72 hours after the injection. Valid data were obtained from 127 patients. Mild systemic reactions varied from 4% to 8% and local reactions varied from 40% to 60%, which is not different from the reported reaction with the initial vaccination. This profile of adverse reactions after revaccination should minimize concerns about revaccination.
肺炎球菌多糖疫苗再接种的适应症包括6年多以前接种过疫苗的高危患者，但对于慢性病患者的再接种以及老年人的再接种存在争议。本研究的目的是调查肺炎球菌多糖疫苗再接种是否会引起严重不良反应。151名患者接受了再接种，并填写了一份关于注射后72小时情况的问卷。从127名患者那里获得了有效数据。轻度全身反应发生率为4%至8%，局部反应发生率为40%至60%，这与初次接种时报告的反应情况并无差异。再接种后的这种不良反应情况应可减少对再接种的担忧。
