Martinez D A, King D R, Romshe C, Lozano R A, Morris J D, O'Dorisio M S, Martin E
Department of Surgery, Ohio State University College of Medicine, Columbus, USA.
J Pediatr Surg. 1995 Sep;30(9):1306-9. doi: 10.1016/0022-3468(95)90491-3.
Technetium 99m-sestamibi, a radiopharmaceutical used for the diagnostic imaging of abnormal parathyroid tissue, and the Neoprobe 1000, a hand-held, gamma-detecting probe, were used concurrently, during surgical exploration, in three children with hyperparathyroidism. This novel combination assisted with the identification of an ectopic mediastinal parathyroid adenoma and with the localization of multiple hyperplastic parathyroid glands. 99mTc-sestamibi combined with the Neoprobe 1000 may prove to be a useful adjunctive technique for the intraoperative localization of abnormal parathyroid tissue in selected patients.
锝99m-甲氧基异丁基异腈,一种用于异常甲状旁腺组织诊断成像的放射性药物,以及Neoprobe 1000,一种手持式伽马探测仪,在手术探查期间同时用于三名甲状旁腺功能亢进的儿童。这种新颖的组合有助于识别异位纵隔甲状旁腺腺瘤以及定位多个增生的甲状旁腺。锝99m-甲氧基异丁基异腈与Neoprobe 1000相结合可能被证明是一种对选定患者术中定位异常甲状旁腺组织有用的辅助技术。