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单心室修复术。早期和中期结果。

Univentricular repair. Early and midterm results.

作者信息

Sharma R, Iyer K S, Airan B, Saha K, Das B, Bhan A, Rao I M, Venugopal P

机构信息

Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi, India.

出版信息

J Thorac Cardiovasc Surg. 1995 Dec;110(6):1692-700; discussion 1700-1. doi: 10.1016/S0022-5223(95)70033-1.

Abstract

A total of 202 patients (62 with tricuspid atresia and 140 without tricuspid atresia) underwent univentricular repair at our unit from January 1990 to September 1994. Of these patients, 182 had nonfenestrated and 20 had fenestrated interatrial baffles. Early mortality was 15.9% (29/182) in the group with nonfenestrated baffles and 5% (1/20) in the group with fenestrated baffles. The follow-up period ranged from 2 to 58 months. Seven late deaths occurred, and five patients were lost to follow-up. Of 160 patients who have been evaluated in the outpatient department in the past 3 months, 142 (88.75%) required no cardiac medicines and were in functional class I. Risk factors analyzed for early mortality and significant effusion were age, preoperative diagnosis, type of Fontan modification, cardiopulmonary bypass time, aortic crossclamp time, pulmonary artery size, associated pulmonary arterioplasty, takedown of systemic-pulmonary artery shunt, and pulmonary artery debanding, along with the Fontan operation. Bypass time exceeding 120 minutes was associated with a higher early mortality (12/47 vs 18/155; p = 0.0187). Bypass time exceeding 120 minutes (p = 0.0456) and aortic crossclamp time exceeding 60 minutes (p = 0.0278) were associated with significant postoperative effusion. Other factors were not associated with any significantly increased risk for early mortality or postoperative effusions. Fenestration of the interatrial baffle appeared to decrease early mortality, although the numbers are too small to be statistically significant. The prevalence of effusions did not differ significantly between the group with fenestrated baffles and the group without fenestrated baffles.

摘要

1990年1月至1994年9月,共有202例患者(62例患有三尖瓣闭锁,140例无三尖瓣闭锁)在我院接受了单心室修复手术。这些患者中,182例采用了无开窗房间隔挡板,20例采用了开窗房间隔挡板。无开窗挡板组的早期死亡率为15.9%(29/182),开窗挡板组为5%(1/20)。随访时间为2至58个月。发生了7例晚期死亡,5例患者失访。在过去3个月接受门诊评估的160例患者中,142例(88.75%)无需服用心脏药物,心功能为I级。对早期死亡率和大量积液的危险因素进行分析的因素包括年龄、术前诊断、Fontan改良类型、体外循环时间、主动脉阻断时间、肺动脉大小、相关的肺动脉成形术、体肺分流的拆除、肺动脉去带术以及Fontan手术。体外循环时间超过120分钟与较高的早期死亡率相关(12/47对比18/155;p = 0.0187)。体外循环时间超过120分钟(p = 0.0456)和主动脉阻断时间超过60分钟(p = 0.0278)与术后大量积液相关。其他因素与早期死亡率或术后积液的任何显著增加风险均无关联。房间隔挡板开窗似乎降低了早期死亡率,尽管数量太少,无统计学意义。开窗挡板组和无开窗挡板组之间积液的发生率无显著差异。

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