Chang K C, Tseng Y Z, Kuo T S, Chen H I
Department of Physiology and Medicine, College of Medicine, National Taiwan University, Taipei.
Med Biol Eng Comput. 1995 Sep;33(5):652-60. doi: 10.1007/BF02510782.
The aortic input impedance is simulated by an asymmetric T-tube model loaded with complex loads. A geometric tapering is incorporated to represent the vasculature, assuming a triangular distribution of the wave transmission paths. Parametric analyses using physiological data demonstrate that the predicted impedance and reflection coefficient spectrum (RCS) closely mimic the experimental data. The simulation also reveals several significant features. As diameter tapering can minimise the presence and influence of wave reflections, the impedance modulus stays relatively constant with two distinct minima. The frequency of first minimum of impedance modulus is evidence of the tube elasticity and load compliance in the lower extremity, and the frequency of second minimum is evidence of those in the upper extremity. The high-frequency portion of the impedance modulus is affected by the tube elasticity, but not by the load compliance. The impedance spectrum at higher frequencies shows no notable fluctuations corresponding to a decrease in blood or wall viscosity. Furthermore, the low-frequency range in RCS is dominated by the longer lower body tube, and the high-frequency range by the shorter upper body tube. This geometrically tapered T-tube is considered a more natural model for the description of the systemic arterial system.
主动脉输入阻抗通过加载复数负载的非对称T型管模型进行模拟。考虑到波传播路径的三角形分布,采用几何渐变来表示脉管系统。使用生理数据进行的参数分析表明,预测的阻抗和反射系数谱(RCS)与实验数据非常相似。模拟还揭示了几个重要特征。由于直径渐变可使波反射的存在和影响最小化,阻抗模量保持相对恒定,有两个明显的最小值。阻抗模量第一个最小值的频率是下肢血管弹性和负载顺应性的体现,第二个最小值的频率是上肢血管弹性和负载顺应性的体现。阻抗模量的高频部分受血管弹性影响,但不受负载顺应性影响。高频下的阻抗谱未显示出与血液或血管壁粘度降低相对应的明显波动。此外,RCS的低频范围主要由较长的下体血管主导,高频范围则由较短的上体血管主导。这种几何渐变的T型管被认为是描述体循环动脉系统更自然的模型。