Dorne L, Alikacem N, Guidoin R, Auger M
Département de Chimie, Université Laval, Québec, Canada.
Magn Reson Med. 1995 Oct;34(4):548-54. doi: 10.1002/mrm.1910340411.
We have used 29Si solid-state nuclear magnetic resonance (NMR) spectroscopy to study the chemical structure of the silicone gels in virgin and explanted breast prostheses. Despite evidences of alteration in the morphological appearance of the silicone gel inside the breast prosthesis, our results do not reveal changes in the chemical nature and structure of the silicone gels after implantation. In addition to the main 29Si resonance peak at -22.26 ppm that corresponds to the resonance frequency of the D repeat unit of the polysiloxane chains, the high sensitivity of our NMR technique allows the detection of very low concentrations of silicone compounds. Within our experimental detection limit of 0.2%, no signal between -90 ppm and -150 ppm are observed. This indicates that no silica products are present inside the gel of the prostheses. Furthermore, our 29Si NMR spectra indicate differences in the chemical compositions of the silicone gels from different manufacturers.
我们利用29Si固态核磁共振（NMR）光谱来研究初次使用的和植入后取出的乳房假体中硅胶凝胶的化学结构。尽管有证据表明乳房假体内部的硅胶凝胶在形态外观上发生了改变，但我们的结果并未揭示植入后硅胶凝胶的化学性质和结构发生了变化。除了在-22.26 ppm处对应于聚硅氧烷链D重复单元共振频率的主要29Si共振峰外，我们的NMR技术的高灵敏度还能够检测到极低浓度的硅化合物。在我们0.2%的实验检测限内，未观察到-90 ppm至-150 ppm之间的信号。这表明假体凝胶内部不存在二氧化硅产物。此外，我们的29Si NMR光谱表明不同制造商生产的硅胶凝胶在化学成分上存在差异。
