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[血液吞噬细胞功能状态在肺结核患者流行性出血热治疗最佳方案选择中的意义]

[Significance of the functional state of blood phagocytes in the choice of optimal regime of EHF therapy of patients with pulmonary tuberculosis].

作者信息

Novikova L N, Kaminskaia G O, Efimova L N

出版信息

Probl Tuberk. 1995(6):17-20.

PMID:8524760
Abstract

A trial entered 136 patients with active tuberculosis of the lungs. 86 patients received conventional chemotherapy and a course of microwave therapy. Control patients received chemotherapy alone. Phagocyte cell viability and NB-test served as assessment laboratory criteria. Millimetric waves in the treatment of pulmonary tuberculosis potentiate the treatment efficacy documented as more rapid infiltration resolution and cavern closure through the mechanism of normalization of phagocyte cell function. The choice of wave length is principal: 5.6 mm waves affect phagocyte function negatively, 6.4 mm waves produce more significant positive effect in young patients with new local lesions while 7.1 mm waves in older patients and in severe involvement. In vitro radiation of the patients' blood using different wave lengths and subsequent performance of NB-test provides objective information for choice of optimal treatment regimen.

摘要

一项试验纳入了136例活动性肺结核患者。86例患者接受了传统化疗和一个疗程的微波治疗。对照组患者仅接受化疗。吞噬细胞活力和硝基蓝四氮唑试验作为评估实验室标准。毫米波治疗肺结核可增强治疗效果,表现为通过吞噬细胞功能正常化机制使浸润吸收和空洞闭合更快。波长的选择至关重要:5.6毫米波长的波对吞噬细胞功能有负面影响,6.4毫米波长的波对有新的局部病灶的年轻患者产生更显著的积极效果,而7.1毫米波长的波对老年患者和病情严重者效果更佳。使用不同波长对患者血液进行体外辐射并随后进行硝基蓝四氮唑试验可为选择最佳治疗方案提供客观信息。

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