Gleadhill A, Peters A M, Michell A R
Department of Large Animal Medicine and Surgery, Royal Veterinary College, North Mymms, Hatfield.
Res Vet Sci. 1995 Sep;59(2):118-23. doi: 10.1016/0034-5288(95)90044-6.
A technique for measuring glomerular filtration rate (by six-sample plasma clearance) and extracellular fluid volume is described. The results obtained for glomerular filtration rat per extracellular fluid volume with a three blood sample technique are also presented. Concurrently with the blood sample techniques measuring plasma clearance, glomerular filtration rate per extracellular fluid volume was also measured using an external radiation detector and no blood samples. The validity of expressing glomerular filtration rate per extracellular fluid volume (rather than per body weight or surface area) and the clinical utility of the results obtained with the external radiation detector are discussed.
本文描述了一种测量肾小球滤过率（通过六样本血浆清除率）和细胞外液量的技术。还给出了采用三血样技术测得的每细胞外液量的肾小球滤过率结果。在采用血样技术测量血浆清除率的同时，还使用外部辐射探测器且不采集血样测量了每细胞外液量的肾小球滤过率。讨论了以每细胞外液量（而非每体重或体表面积）表示肾小球滤过率的有效性以及用外部辐射探测器获得的结果的临床实用性。
