Gaboury C L, Woods L L
Division of Nephrology, Hypertension, and Clinical Pharmacology, Oregon Health Sciences University, Portland 97201-3098, USA.
Semin Nephrol. 1995 Sep;15(5):449-53.
Normal pregnancy is associated with increases in renal blood flow and glomerular filtration rate, increases that are probably the most dramatic seen under any physiological conditions. Yet, despite these marked elevations in baseline values, most investigators have found that the kidneys of pregnant animals and humans are capable of further vasodilation and hyperfiltration in response to an acute protein load or amino acid infusion, ie, renal reserve is maintained in pregnancy.
正常妊娠与肾血流量和肾小球滤过率增加相关，这种增加可能是在任何生理条件下所见到的最显著的变化。然而，尽管基线值有这些明显升高，但大多数研究人员发现，怀孕动物和人类的肾脏在应对急性蛋白质负荷或氨基酸输注时仍能够进一步血管舒张和超滤过，也就是说，妊娠期间肾脏储备功能得以维持。
