Woods L L
Division of Nephrology, Hypertension, and Clinical Pharmacology, Oregon Health Sciences University, Portland 97201-3098, USA.
Semin Nephrol. 1995 Sep;15(5):386-95.
Acute ingestion of protein and intravenous infusion of amino acids are known to stimulate increases in renal blood flow and glomerular filtration rate (GFR) in animals and humans. Although some investigators believe that these changes are mediated by a circulating hormonal factor, there is considerable evidence that intrinsic intrarenal mechanisms such as tubular transport of amino acids and sodium, and the tubuloglomerular feedback mechanism, are involved in this renal hemodynamic response, and that extrarenal factors may not be required.
已知在动物和人类中，急性摄入蛋白质和静脉输注氨基酸会刺激肾血流量和肾小球滤过率（GFR）增加。尽管一些研究人员认为这些变化是由循环激素因子介导的，但有大量证据表明，肾内固有机制，如氨基酸和钠的肾小管转运以及肾小管-肾小球反馈机制，参与了这种肾血流动力学反应，并且可能不需要肾外因素。
