Ibarra H, Riedemann S, Mezzano S, Toledo C, Reinhardt G, Núñez M, Becker J, Froesner G
Instituto de Medicina y Microbiología, Universidad Austral de Chile, Valdivia, Chile.
Rev Med Chil. 1995 Apr;123(4):439-44.
The aim of this study was to determine the prevalence of hepatitis C virus antibodies in high risk patients coming from Valdivia, Osorno and Puerto Montt. Fifty-six patients in hemodialysis, 51 renal graft recipients, 42 cirrhotics and 14 patients with acute non A non B hepatitis were studied. Antibodies were detected with a second generation ELISA technique and positive cases were confirmed with RIBA. All hemodialysis patients and renal graft recipients were negative for hepatitis C virus antibodies. In one non alcoholic patient with cirrhosis, a positive ELISA was confirmed with RIBA. Six patients with acute hepatitis had positive ELISA tests but none was confirmed with RIBA. It is concluded that the prevalence of hepatitis C virus antibodies in this region of Chile is very low.
本研究旨在确定来自瓦尔迪维亚、奥索尔诺和蒙特港的高危患者中丙型肝炎病毒抗体的流行情况。对56例血液透析患者、51例肾移植受者、42例肝硬化患者和14例急性非甲非乙型肝炎患者进行了研究。采用第二代酶联免疫吸附测定（ELISA）技术检测抗体，并用重组免疫印迹法（RIBA）确认阳性病例。所有血液透析患者和肾移植受者的丙型肝炎病毒抗体均为阴性。在1例非酒精性肝硬化患者中，ELISA检测呈阳性，经RIBA确认。6例急性肝炎患者ELISA检测呈阳性，但经RIBA确认均为阴性。结论是，智利该地区丙型肝炎病毒抗体的流行率非常低。
