Zainal D, Riduan A, Ismail A M, Norhayati O
Department of Medicine, Universiti Sains Malaysia Hospital, Kubang Kerian, Kelantan, Malaysia.
Southeast Asian J Trop Med Public Health. 1995 Mar;26(1):149-53.
Renal biopsy is essential in the management of renal parenchymal diseases. Thus far there is no publish report on the pattern of glomerulonephritis in Kelantan. We decided to establish the pattern of glomerulonephritis in Kelantan and use this information as our reference in future studies. Records of patients who had proven glomerulonephritis histologically were analysed. Their biological data, clinical presentation, etiology and clinicopathological pattern were studied. Where appropriate mean and standard deviation were calculated. A total of 74 biopsies were performed during the study period (between January 1991 and December 1993), out of which 72 biopsies (97.3%) were considered suitable for analysis. The male to female ratio was 1:1.1. Mean age at presentation was 27.6 +/- 12.2 years. Nephrotic syndrome was the commonest clinical presentation (65.3%). The main underlying cause was systemic lupus erythematosus (50%) followed by primary glomerulonephritis. Histologically, IgA nephropathy and minimal change disease were the main patterns among patients with primary glomerulonephritis while diffuse proliferative glomerulonephritis was the commonest pattern among patients with lupus nephritis. Hence the pattern of glomerulonephritis is similar to other reported series. The procedure is considered safe and has a high success rate.
肾活检对于肾实质疾病的管理至关重要。迄今为止，关于吉兰丹州肾小球肾炎模式尚无发表的报告。我们决定确定吉兰丹州肾小球肾炎的模式，并将此信息作为我们未来研究的参考。对经组织学证实患有肾小球肾炎的患者记录进行了分析。研究了他们的生物学数据、临床表现、病因和临床病理模式。在适当情况下计算了均值和标准差。在研究期间（1991年1月至1993年12月）共进行了74例活检，其中72例活检（97.3%）被认为适合分析。男女比例为1:1.1。就诊时的平均年龄为27.6±12.2岁。肾病综合征是最常见的临床表现（65.3%）。主要潜在病因是系统性红斑狼疮（50%），其次是原发性肾小球肾炎。组织学上，IgA肾病和微小病变病是原发性肾小球肾炎患者的主要模式，而弥漫性增殖性肾小球肾炎是狼疮性肾炎患者最常见的模式。因此，肾小球肾炎的模式与其他报告系列相似。该操作被认为是安全的，成功率很高。
