Deshpande G U, Munjal Rachna, Rai Ramji
Reader, Department of Pathology, Armed Forces Medical College, Pune 411 040.
Post Graduate Student, Department of Pathology, Armed Forces Medical College, Pune 411 040.
Med J Armed Forces India. 2000 Apr;56(2):125-129. doi: 10.1016/S0377-1237(17)30127-2. Epub 2017 Jun 10.
A retrospective study was carried out where histopathology records of Department of Pathology, Armed Forces Medical College, Pune were scrutinised covering a period of 10 years. We came across 325 cases of nephropathies. The sample comprised of 92.6% adults and 7.4% children. 79.7% were males and 20.3% were females. The patient population comprised of 35.1% serving soldiers, 37.8% their family members and 27.1% not related to Armed Forces. The study is based on only light microscopy findings. It was observed that primary glomerular disease was the commonest entity and comprised of 61.5% of all the nephropathies. Acute diffuse proliferative glomerulonephritis was not only the commonest primary glomerulopathy (23.5%) but the commonest nephropathy as well. The other primary glomerulopathies in descending order of frequency were, membranoproliferative glomerulonephritis (22.5%), mesangioproliferative glomerulonephritis (21.5%), chronic glomerulonephritis (9%), minimal change disease (7.5%), membranous glomerulopathy (7%), focal segmental glomerulosclerosis (5%) and crescentic glomerulonephritis (4%). We had only 14 cases (4.3% of all nephropathies) of secondary glomerulopathies, amongst which amyloidosis was the commonest cause. We came across 2 cases (0.6% of all nephropathies) of Alport's syndrome. In the other nephropathies, 22.2% were tubulointerstitial diseases and 5.5% were malignant kidney tumors. In 5.8% renal biopsies, no significant pathology was seen on light microscopy.
开展了一项回顾性研究，对浦那武装部队医学院病理科10年间的组织病理学记录进行了审查。我们共发现325例肾病病例。样本中成人占92.6%，儿童占7.4%。男性占79.7%，女性占20.3%。患者群体包括35.1%的现役军人、37.8%的军人家属以及27.1%与武装部队无关的人员。该研究仅基于光学显微镜检查结果。观察发现，原发性肾小球疾病是最常见的类型，占所有肾病的61.5%。急性弥漫性增生性肾小球肾炎不仅是最常见的原发性肾小球病（23.5%），也是最常见的肾病。其他原发性肾小球病按频率递减顺序依次为：膜增生性肾小球肾炎（22.5%）、系膜增生性肾小球肾炎（21.5%）、慢性肾小球肾炎（9%）、微小病变病（7.5%）、膜性肾小球病（7%）、局灶节段性肾小球硬化（5%）和新月体性肾小球肾炎（4%）。我们仅有14例继发性肾小球病（占所有肾病的4.3%），其中淀粉样变性是最常见的病因。我们发现2例Alport综合征（占所有肾病的0.6%）。在其他肾病中，22.2%为肾小管间质性疾病，5.5%为肾恶性肿瘤。在5.8%的肾活检中，光学显微镜检查未发现明显病变。
