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马来西亚蚊虫的谷胱甘肽 S-转移酶活性与滴滴涕易感性

Glutathion S-transferase activity and DDT-susceptibility of Malaysian mosquitos.

作者信息

Lee H L, Chong W L

机构信息

Division of Medical Entomolgy, Institute for Medical Research, Jalan Pahang, Kuala Lumpur, Malaysia.

出版信息

Southeast Asian J Trop Med Public Health. 1995 Mar;26(1):164-7.

PMID:8525405
Abstract

Comparative DDT-susceptibility status and glutathion s-transferase (GST) activity of Malaysian Anopheles maculatus, Culex quinquefasciatus and Aedes aegypti was investigated to ascertain the role of this enzyme in DDT resistance. The standardised WHO dose-mortality bioassay tests were used to determine DDT susceptibility in these mosquitos, whilst GST microassay (Brogdon and Barber, 1990) was conducted to measure the activity of this enzyme in mosquito homogenate. It appeared that DDT susceptibility status of Malaysian mosquitos was not correlated with GST activity.

摘要

研究了马来西亚多斑按蚊、致倦库蚊和埃及伊蚊对滴滴涕的易感性状况及谷胱甘肽 - S - 转移酶(GST)活性,以确定该酶在滴滴涕抗性中的作用。采用标准化的世卫组织剂量 - 死亡率生物测定试验来确定这些蚊子对滴滴涕的易感性,同时进行GST微量测定(Brogdon和Barber,1990)以测量蚊子匀浆中该酶的活性。结果表明,马来西亚蚊子对滴滴涕的易感性状况与GST活性无关。

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