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[麻醉性质药物影响下大鼠脑ATP酶水解ATP过程中的化学发光]

[Chemoluminescence during ATP hydrolysis by rat brain ATPase under the influence of agents of a narcotic nature].

作者信息

Vagin Iu E, Kovrizhnykh V A

出版信息

Farmakol Toksikol. 1977 Jan-Feb;40(1):28-31.

PMID:852542
Abstract

The activity of the cerebral ATP-ase and chemoluminescence in hydrolysis of the ATP with the cerebral ATP-ase in rats with ether, thiopental and electrically-induced anesthesia was investigated. In the ether anesthesis the ATP-ase activity and the chemoluminescence level decrease. In the thiopental anesthesia they increase, whereas with electrically-induced one they first go up and then fall off. Once the action of the study agents is discontinued the mentioned parameters return back to their control levels.

摘要

研究了在乙醚、硫喷妥钠和电诱导麻醉的大鼠中,脑ATP酶活性以及脑ATP酶水解ATP时的化学发光情况。在乙醚麻醉下,ATP酶活性和化学发光水平降低。在硫喷妥钠麻醉下,它们升高,而在电诱导麻醉下,它们先升高然后下降。一旦停止研究药物的作用,上述参数就会恢复到对照水平。

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