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[麻醉性质药物影响下大鼠脑ATP酶水解ATP过程中的化学发光]

[Chemoluminescence during ATP hydrolysis by rat brain ATPase under the influence of agents of a narcotic nature].

作者信息

Vagin Iu E, Kovrizhnykh V A

出版信息

Farmakol Toksikol. 1977 Jan-Feb;40(1):28-31.

PMID:852542
Abstract

The activity of the cerebral ATP-ase and chemoluminescence in hydrolysis of the ATP with the cerebral ATP-ase in rats with ether, thiopental and electrically-induced anesthesia was investigated. In the ether anesthesis the ATP-ase activity and the chemoluminescence level decrease. In the thiopental anesthesia they increase, whereas with electrically-induced one they first go up and then fall off. Once the action of the study agents is discontinued the mentioned parameters return back to their control levels.

摘要

研究了在乙醚、硫喷妥钠和电诱导麻醉的大鼠中,脑ATP酶活性以及脑ATP酶水解ATP时的化学发光情况。在乙醚麻醉下,ATP酶活性和化学发光水平降低。在硫喷妥钠麻醉下,它们升高,而在电诱导麻醉下,它们先升高然后下降。一旦停止研究药物的作用,上述参数就会恢复到对照水平。

相似文献

1
[Chemoluminescence during ATP hydrolysis by rat brain ATPase under the influence of agents of a narcotic nature].[麻醉性质药物影响下大鼠脑ATP酶水解ATP过程中的化学发光]
Farmakol Toksikol. 1977 Jan-Feb;40(1):28-31.
2
[Inhibitory activity of rat brain lipids during exposure to agents of a anesthetic nature].[大鼠脑脂质在暴露于麻醉性质药物期间的抑制活性]
Nauchnye Doki Vyss Shkoly Biol Nauki. 1977(3):29-33.
3
Thyroxine distribution during ether and thiopental anesthesia in man.人体在乙醚和硫喷妥钠麻醉期间甲状腺素的分布情况。
Anesth Analg. 1969 Jan-Feb;48(1):1-6.
4
[The impedance of the cerebral cortex under different types of anesthesia].[不同类型麻醉下大脑皮层的阻抗]
Neirofiziologiia. 1971 May-Jun;3(3):260-5.
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[The effect of thiopental sodium and ether anesthesia on the processes of leukocytolysis and phagocytosis in various vascular areas].[硫喷妥钠和乙醚麻醉对不同血管区域白细胞溶解和吞噬过程的影响]
Zh Mikrobiol Epidemiol Immunobiol. 1966 Mar;43(3):138-43.
6
[Effects of general anesthesia on plasma thyroxine levels in man].[全身麻醉对人体血浆甲状腺素水平的影响]
Masui. 1968 Sep;17(9):842-8.
7
[Characteristics of the effect of ether, sodium thiopental, fentanyl and naloxone on respiration].[乙醚、硫喷妥钠、芬太尼及纳洛酮对呼吸作用的特点]
Farmakol Toksikol. 1983 Mar-Apr;46(2):31-6.
8
Survival and neurological outcome of the Mongolian gerbil with or without bilateral carotid ligation after treatment with ether, thiopental or etomidate.
Arch Int Pharmacodyn Ther. 1983 Jun;263(2):314-6.
9
Some metabolic changes associated with anesthesia and operation.一些与麻醉和手术相关的代谢变化。
Surg Clin North Am. 1969 Apr;49(2):223-31. doi: 10.1016/s0039-6109(16)38781-3.
10
[Influence of duration and depth of ether of brevinarcon narcosis on the cerebral acetylcholine content of rat].[溴米那普鲁卡因麻醉的持续时间和深度对大鼠脑内乙酰胆碱含量的影响]
Acta Biol Med Ger. 1978;37(4):681-4.

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