Erosive and ulcerative skin disease.

Many causes exist for ulcerative disease of the skin and mucous membranes of cats. History, physical examination, cytology, skin biopsy, a hemogram, serum biochemical evaluation, and FeLV and feline immunodeficiency virus testing are a standard diagnostic protocol for such cases. Therapy is dependent on the underlying cause. Symptomatic therapy consisting of cleansing soaks (chlorhexidine) and systemic antibiotics (trimethoprim-sulfadiazine or amoxicillin-clavulanic acid) may be helpful to control secondary bacterial infections. If ulceration is widespread, serum leakage may result in a decreased total protein and more systemic signs. When oral ulcers are present, food and water consumption may be affected. Enteral nutrition may be helpful to sustain the cat during the diagnostic workup or until results of treatment are evident.