Favrot C, Wilhelm S, Grest P, Meli M L, Hofmann-Lehmann R, Kipar A
Clinic for Small Animal Internal Medicine, Dermatology Unit, Universit of Zürich, Zürich, Switzerland.
Vet Dermatol. 2005 Dec;16(6):407-12. doi: 10.1111/j.1365-3164.2005.00480.x.
Two cases of feline leukaemia virus (FeLV)-associated dermatosis are described. The first cat was affected by an ulcerative dermatitis identified as a giant-cell dermatosis. The second case was a cutaneous lymphoma. In both cases, FeLV antigens and FeLV genome were demonstrated in the affected skin immunologically and with polymerase chain reaction, respectively. The first case suggests that, like other retroviruses, at least some strains of FeLV can induce syncytium formation. As FeLV antigens and genome were demonstrated in a serologically negative cat, the second case suggests that focal skin FeLV replication may occur. FeLV-associated dermatoses are rare skin conditions that may be under-diagnosed.
本文描述了两例猫白血病病毒（FeLV）相关的皮肤病。第一只猫患有溃疡性皮炎，经鉴定为巨细胞性皮肤病。第二例是皮肤淋巴瘤。在这两例中，分别通过免疫方法和聚合酶链反应在患病皮肤中检测到了FeLV抗原和FeLV基因组。第一例表明，与其他逆转录病毒一样，至少某些FeLV毒株可诱导多核巨细胞形成。由于在一只血清学检测呈阴性的猫身上检测到了FeLV抗原和基因组，第二例提示可能发生了局灶性皮肤FeLV复制。FeLV相关的皮肤病是罕见的皮肤疾病，可能未得到充分诊断。
