[硬皮病中的细胞免疫现象]
[Cellular immune phenomenon in scleroderma].
作者信息
Fritz J, Sandhofer M
出版信息
Dermatologica. 1977;154(3):129-37.
The leucocyte-migration-inhibition test was performed to examine 10 patients with progressive systemic sclerosis and 6 patients with linear scleroderma for evidence of cell-mediated immunity to RNA, DNA, human muscle antigen and collagen human type I. An inhibition of cell migration was detected in 6 patients with progressive systemic sclerosis (PSS) and in 3 patients with linear scleroderma in presence of RNA. No cellular reactivity in presence of DNA was observed. Seven cases with PSS, and all 6 cases with linear scleroderma showed a migration inhibition when human muscle antigen was tested. Cell-mediated immunity to collagen human type I was discovered 7 times in PSS and 2 times in linear scleroderma.
进行白细胞游走抑制试验，以检测10例进行性系统性硬化症患者和6例线状硬皮病患者对RNA、DNA、人肌肉抗原和I型人胶原蛋白的细胞介导免疫证据。在存在RNA的情况下，6例进行性系统性硬化症（PSS）患者和3例线状硬皮病患者检测到细胞游走受到抑制。在存在DNA的情况下未观察到细胞反应性。检测人肌肉抗原时，7例PSS患者和所有6例线状硬皮病患者均表现出游走抑制。在PSS中发现7次对I型人胶原蛋白的细胞介导免疫，在线状硬皮病中发现2次。
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