Cougard P, Calender A, Carnaille B, Beckers A, Cadiot G, Chanson P, Chayvialle J A, Conte-Devolx B, Decoulx M, Henry J F
Service de Chirurgie Générale et Endocrinienne, Hôpital Général, CHRU, Dijon.
Ann Chir. 1995;49(6):500-6.
The "Groupe d'Etude des Néoplasies Endocriniennes Multiples de type 1 (GENEM 1)" is a French group involved in a comprehensive multicentre study of Multiple Endocrine Neoplasia type 1 syndrome (NEM 1). The objectives of this group are to define diagnostic and therapeutic protocols and to carry out genetic research on NEM1. The first aim of physicians is to recognize the syndrome and to determine the appropriate screening especially into two circumstances: 1 degree In case of isolated and sporadic glandular disease -i-e-parathyroid glands, endocrine pancreas, antehypophysis, adrenal glands and neuroendocrine tumors? 2 degrees In case of very high probability of NEM 1 syndrome? This paper answers these two questions, based on the analysis of the first 150 cases collected by the GENEM 1.
“1型多发性内分泌肿瘤研究小组（GENEM 1）”是一个法国团队，参与了一项关于1型多发性内分泌肿瘤综合征（NEM 1）的全面多中心研究。该小组的目标是确定诊断和治疗方案，并对NEM1进行基因研究。医生的首要目标是识别该综合征，并确定适当的筛查方法，特别是在以下两种情况下：1度，在孤立性和散发性腺体疾病（即甲状旁腺、内分泌胰腺、垂体前叶、肾上腺和神经内分泌肿瘤）的情况下？2度，在NEM 1综合征可能性非常高的情况下？本文基于对GENEM 1收集的前150例病例的分析，回答了这两个问题。
