Kempner E S
Laboratory of Physical Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Bull Math Biol. 1995 Nov;57(6):883-98. doi: 10.1007/BF02458298.
Radiation target theory has been extended to complex biochemical systems. Mathematical analyses are presented for multiple forms of biological active proteins, for the presence of large inhibitors or activators, for compounds which regulate rate or affinity and for multiple-step reactions. Several predictions of these models have been verified experimentally.
辐射靶理论已扩展到复杂的生化系统。本文针对多种形式的生物活性蛋白、存在大的抑制剂或激活剂、调节速率或亲和力的化合物以及多步反应进行了数学分析。这些模型的几个预测已通过实验得到验证。