Renner H
Fortschr Med. 1977 Feb 24;95(8):510-2.
Experiments on radiosensitivity of lymphocyte stimulation in vitro and in vivo are described. Mainly the effects on DNA-synthesis and mitotic activity were measured. The effects of delay and inhibition are not specific for stimulated lymphocyte populations, they are common radiobiological characteristics of stimulated proliferation in contrast to spontaneous proliferation. Cells under stimulated proliferation are more radioresistant than the same cells without stimulation or other cells under spontaneous proliferation. In these basic and additional experiments lymphocyte stimulation proved to be a good radiobiological model system.
本文描述了关于淋巴细胞在体外和体内放射敏感性的实验。主要测量了对DNA合成和有丝分裂活性的影响。延迟和抑制效应并非受刺激淋巴细胞群体所特有，与自发增殖相比，它们是受刺激增殖的常见放射生物学特征。处于受刺激增殖状态的细胞比未受刺激的相同细胞或处于自发增殖状态的其他细胞对辐射更具抗性。在这些基础和补充实验中，淋巴细胞刺激被证明是一个良好的放射生物学模型系统。
