耶尔森氏菌中基因表达的环境调控与发病机制
Environmental modulation of gene expression and pathogenesis in Yersinia.
作者信息
Straley S C, Perry R D
机构信息
Dept of Microbiology and Immunology, University of Kentucky, Lexington 40536-0084, USA.
出版信息
Trends Microbiol. 1995 Aug;3(8):310-7. doi: 10.1016/s0966-842x(00)88960-x.
PMID:8528615
Abstract
The yersiniae are a useful model for understanding how environmental modulation of gene expression allows pathogens to inhabit a wide range of niches. This review follows the enteropathogenic yersiniae, Yersinia enterocolitica and Yersinia pseudotuberculosis, and the agent of plague, Yersinia pestis, through their life cycles, describing how adaptive gene expression may promote successful pathogenesis.
摘要
耶尔森氏菌是理解基因表达的环境调节如何使病原体占据广泛生态位的有用模型。本综述追踪肠道致病性耶尔森氏菌（小肠结肠炎耶尔森氏菌和假结核耶尔森氏菌）以及鼠疫病原体鼠疫耶尔森氏菌的生命周期，描述适应性基因表达如何促进成功的致病过程。
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