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孤立性脑栓塞与克罗恩病

Isolated cerebral thrombo-embolism and Crohn disease.

作者信息

Gormally S M, Bourke W, Kierse B, Monaghan H, McMenamin J, Drumm B

机构信息

Department of Paediatrics, University College Dublin, Ireland.

出版信息

Eur J Pediatr. 1995 Oct;154(10):815-8. doi: 10.1007/BF01959788.

Abstract

Arterial thrombo-embolism is an unusual complication in inflammatory bowel disease in adults and children. Cerebral arterial disease has been reported on only a few occasions. There are only two previous case reports of arterial disease occurring in a child with Crohn disease. However in both instances the arterial disease was part of a generalised Takayasu arteritis which resulted in multi-organ involvement. This report describes a 14-year-old boy who developed seizures before a histological diagnosis of Crohn disease was made. These seizures were the result of a vascular lesion which was confined to the right middle cerebral artery. CONCLUSION. Crohn disease as well as ulcerative colitis should be considered as a possible cause of cerebrovascular accidents in children.

摘要

动脉血栓栓塞在成人和儿童的炎症性肠病中是一种不常见的并发症。脑动脉疾病仅在少数情况下有报道。此前仅有两例关于患有克罗恩病的儿童发生动脉疾病的病例报告。然而在这两个病例中,动脉疾病都是全身性大动脉炎的一部分,导致多器官受累。本报告描述了一名14岁男孩,在克罗恩病组织学诊断之前出现癫痫发作。这些癫痫发作是由局限于右侧大脑中动脉的血管病变引起的。结论。克罗恩病以及溃疡性结肠炎应被视为儿童脑血管意外的可能病因。

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