Usuda T
Division of Dermatology, Social Insurance Chukyo Hospital.
Nihon Rinsho. 1995 Oct;53(10):2557-62.
Eight cases of Sjögren syndrome (SjS) with anti-SS-A and anti-SS-B antibodies are reported. They developed erythema annulare centrifugum-like annular erythema which mainly appeared on the face. Laboratory tests showed similar serologic changes. RA factor, speckled type antinuclear antibody, anti SS-A & SS-B antibodies (DID & ELISA) were observed but complements and anti-double stranded DNA antibodies were not detected. In spite of mild sicca symptoms, sialogram, lip biopsy, Shirmer test and Rose Bengal staining showed typical changes of SjS. It is considered that the recurrent annular erythema is a specific skin manifestation of SjS with anti SS-A/SS-B antibodies.
报告了8例伴有抗SS - A和抗SS - B抗体的干燥综合征（SjS）病例。他们出现了主要出现在面部的离心性环状红斑样环形红斑。实验室检查显示出相似的血清学变化。观察到类风湿因子、斑点型抗核抗体、抗SS - A和抗SS - B抗体（双扩散免疫电泳法和酶联免疫吸附测定法），但未检测到补体和抗双链DNA抗体。尽管有轻度干燥症状，但唾液造影、唇活检、泪液分泌试验和玫瑰红染色显示出干燥综合征的典型变化。认为复发性环形红斑是伴有抗SS - A/SS - B抗体的干燥综合征的一种特异性皮肤表现。
