Mitchell G F, Garcia E G, Davern K M, Tiu W U
CSL Limited, Parkville, Victoria, Australia.
Mem Inst Oswaldo Cruz. 1995 Mar-Apr;90(2):293-5. doi: 10.1590/s0074-02761995000200030.
The hypothesis that granuloma modulation and disease abatement in chronic infection with Schistosoma japonicum could be ascribed to antibody-mediated effects on egg maturation and egg viability, arose from studies performed with mice in the Philippines. This novel hypothesis has not yet been integrated into the schistosomiasis literature despite being formulated more than a decade ago. One reason for this is that the phenomenon might be confined to S. japonicum, even S. japonicum (Philippines).
日本血吸虫慢性感染中肉芽肿调节和疾病减轻可归因于抗体对虫卵成熟和虫卵活力的介导作用这一假说,源于在菲律宾对小鼠进行的研究。尽管这一新颖的假说早在十多年前就已提出,但尚未被纳入血吸虫病文献中。原因之一可能是该现象可能仅限于日本血吸虫,甚至是日本血吸虫(菲律宾株)。