Zhu J Y, Li Y H
Department of Parasitology, Suzhou Medical College.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1990;8(4):277-80.
The IEST using both liver tissue-egg frozen section of mice infected with Schistosoma japonicum and adult worm frozen section of Schistosoma japonicum (TEFS-IEST and AWFS-IEST) were performed to study the dynamics of specific antibodies in sera from rabbits infected with unisexual and bisexual cercariae of Schistosoma japonicum. Both peaks of specific antibodies appeared at the 10th week after infection. The levels of specific antibodies were much higher in bisexual infection than in unisexual infection and closely related to the intensity and duration of infection. The levels of anti-egg antibodies were higher than those of anti-adult worm antibodies. The serological reactivity of egg antigen is higher than that of adult worm antigen. TEFS-IEST shows higher sensitivity and specificity than AWFS-IEST and DGS-COPT for the diagnosis of schistosomiasis.
采用日本血吸虫感染小鼠肝组织虫卵冰冻切片和日本血吸虫成虫冰冻切片的间接酶标球蚴沉淀试验（TEFS-IEST和AWFS-IEST），研究感染日本血吸虫单性和两性尾蚴的家兔血清中特异性抗体的动态变化。特异性抗体的两个峰值均出现在感染后第10周。两性感染时特异性抗体水平远高于单性感染，且与感染强度和持续时间密切相关。抗虫卵抗体水平高于抗成虫抗体水平。虫卵抗原的血清学反应性高于成虫抗原。在血吸虫病诊断中，TEFS-IEST比AWFS-IEST和DGS-COPT具有更高的敏感性和特异性。
