Rondanelli M, Minoli L
Minerva Endocrinol. 1995 Jun;20(2):113-26.
A number of studies confirm that any human tissue can be targeted by HIV, and also the endocrine system is involved during HIV infection. No endocrine adenus is saved by the assault of the opportunistic pathogens that overrun the organism unprotected due to the severe and progressive immune deficits induced by the HIV. As a consequence clinical, but often subclinical alterations can be detected that underline the close relationship among the systems of body adaptation to the environment (immune, endocrine, and nervous). Indeed these alterations can be viewed as an immunoneuroendocrine pathology. AIDS is a paradigmatic syndrome for the variety of immune dysfunctions, and also presents endocrine and neurological dysfunctions, which allow to better understand the connections among these systems, and the interactions of HIV with the immunoneuroendocrine dynamics.
多项研究证实，HIV可侵袭任何人体组织，而且在HIV感染过程中内分泌系统也会受累。由于HIV导致严重且进行性的免疫缺陷，机体失去保护，机会性病原体的侵袭使得内分泌腺无一幸免。因此，可检测到临床症状，但往往是亚临床改变，这突出了机体适应环境的系统（免疫、内分泌和神经）之间的密切关系。实际上，这些改变可被视为一种免疫神经内分泌病理学。艾滋病是免疫功能障碍多样性的典型综合征，还存在内分泌和神经功能障碍，这有助于更好地理解这些系统之间的联系，以及HIV与免疫神经内分泌动态的相互作用。
