[Interrelations of disorders of the endocrine and immune systems of patients with malignant melanoma].

Investigations of endocrine and immune systems in melanoma patients gave evidence that such patients develop disorders of functions between thymus, on the one hand, and those of the pineal gland, pituitary, adrenal cortex and gonads, on the other, which are important in the pathogenesis of alterations in cell-mediated and humoral immune responses. The author recommends the administration to melanoma patients of either preparations of thymus itself or those with thymosin-like activity, as well as biologically active factors of the pineal gland which normalize metabolic changes in the body.