旅行者疑似疟疾的备用治疗。

Stand-by treatment of suspected malaria in travellers.

作者信息

Nothdurft H D, Jelinek T, Pechel S M, Hess F, Maiwald H, Marschang A, von Sonnenburg F, Weinke T, Löscher T

机构信息

Department of Infectious Diseases and Tropical Medicine, University of Munich, Germany.

出版信息

Trop Med Parasitol. 1995 Sep;46(3):161-3.

PMID:8533018

Abstract

Travellers to malarious areas are increasingly advised to carry an emergency medication for self-treatment of suspected malaria in absence of medical attention. However, no data are available so far how travellers cope with self-diagnosis and stand by treatment (SBT). We therefore investigated the frequency, circumstances and outcome of emergency self-treatment for suspected malaria in German travellers. 3434 travellers were recruited for an open prospective study by 28 different travel clinics in Germany. 2867 travellers (90.1%) who returned questionnaires after their journey were analyzed. 40 travellers (1.4%) reported about SBT during their journey. Significant Plasmodium falciparum antibody levels could be demonstrated in only 4 of 37 SBT users (10.4%). In another 127 travellers with febrile episodes but without SBT use, no malaria was indicated by follow-up and/or serology.

摘要

越来越多的人建议前往疟疾流行地区的旅行者随身携带应急药物，以便在无法获得医疗救治时对疑似疟疾进行自我治疗。然而，目前尚无关于旅行者如何进行自我诊断以及备用治疗（SBT）情况的数据。因此，我们对德国旅行者针对疑似疟疾进行紧急自我治疗的频率、情况及结果展开了调查。德国28家不同的旅行诊所招募了3434名旅行者参与一项开放性前瞻性研究。对2867名在旅行结束后返回问卷的旅行者（90.1%）进行了分析。40名旅行者（1.4%）报告在旅行期间进行了备用治疗。在37名备用治疗使用者中，仅有4人（10.4%）的恶性疟原虫抗体水平呈阳性。在另外127名有发热症状但未进行备用治疗的旅行者中，随访和/或血清学检查均未显示感染疟疾。