Takayanagi T, Fukuda M, Tsuji Y, Nakazawa M
Department of Pediatrics, Nagasaki University School of Medicine, Japan.
Acta Paediatr Jpn. 1995 Oct;37(5):594-8. doi: 10.1111/j.1442-200x.1995.tb03383.x.
The purpose of the present study was to evaluate the usefulness of cutaneous microcirculatory monitoring during hemorrhage. We observed changes in cutaneous blood volume, velocity and flow of five adult rabbits during hemorrhage by using a laser Doppler flowmetry. Mean arterial blood pressure, heart rate and blood gas values were measured. Cutaneous blood volume, velocity and flow decreased significantly after drawing 10 mL/kg of blood, while heart rate, mean arterial blood pressure and blood gas did not change. The decrease of cutaneous blood velocity preceded that of blood volume and was associated more deeply with the reduction of blood flow. In conclusion, cutaneous microcirculatory monitoring using laser Doppler flowmetry is a sensitive technique for detecting early changes of circulatory failure caused by hemorrhage.
本研究的目的是评估出血期间皮肤微循环监测的实用性。我们使用激光多普勒血流仪观察了5只成年兔在出血过程中皮肤血容量、血流速度和血流量的变化。测量了平均动脉血压、心率和血气值。抽取10 mL/kg血液后，皮肤血容量、血流速度和血流量显著下降，而心率、平均动脉血压和血气值未发生变化。皮肤血流速度的下降先于血容量的下降，且与血流量的减少关联更为密切。总之，使用激光多普勒血流仪进行皮肤微循环监测是检测出血引起的循环衰竭早期变化的一种敏感技术。
